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1

Increased sensitivity of BRCA defective triple negative breast tumors to plumbagin through induction of DNA Double Strand Breaks (DSB)

Nair, Rakesh Sathish, Kumar, Jerald Mahesh, Jose, Jedy, Somasundaram, Veena, Hemalatha, Sreelatha K., Sengodan, Satheesh Kumar, Nadhan, Revathy, Anilkumar, Thapasimuthu V., Srinivas, Priya

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

2

Insights into the targeted elimination of BRCA1-defective cancer stem cells

Veena Somasundaram, Priya Srinivas

Journal:

Medicinal Research Reviews

Year:

2012

Language:

english

File:

PDF, 392 KB

english, 2012

3

Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo

Sutapa Sinha, Krishnendu Pal, Ahmed Elkhanany, Shamit Dutta, Ying Cao, Gourish Mondal, Seethalakshmi Iyer, Veena Somasundaram, Fergus J. Couch, Viji Shridhar, Resham Bhattacharya, Debabrata Mukhopadhy

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

4

Structure activity relationship of plumbagin in BRCA1 related cancer cells

K.A. Thasni, T. Ratheeshkumar, G. Rojini, K.C. Sivakumar, Nair Rakesh Sathish, G. Srinivas, Banerji Asoke, Somasundaram Veena, Srinivas Priya

Journal:

Molecular Carcinogenesis

Year:

2012

Language:

english

File:

PDF, 967 KB

english, 2012

5

The molecular response of vanadium complexes of nicotinoyl hydrazone in cervical cancers—A possible interference with HPV oncogenic markers

Nair, Rakesh S., Kuriakose, Mini, Somasundaram, Veena, Shenoi, Vinesh, Kurup, M.R. Prathapachandra, Srinivas, Priya

Journal:

Year:

2014

Language:

english

File:

PDF, 1.30 MB

english, 2014

6

Plumbagin, a naphthaquinone derivative induces apoptosis and in BRCA 1/2 defective castrate resistant prostate cancer cells as well as prostate cancer stem-like cells

Reshma, R.S., Sreelatha, K.H., Somasundaram, Veena, Satheesh, S. Kumar, Revathy,, Nair, Rakesh Sathish, Srinivas, Priya

Journal:

Pharmacological Research

Year:

2016

Language:

english

File:

PDF, 1.96 MB

english, 2016

7

Nitric Oxide and Reactive Oxygen Species: Clues to target Oxidative Damage Repair Defective Breast Cancers

Somasundaram, Veena, Nadhan, Revathy, Sreelatha, K.H., Kumar, S.Satheesh, Srinivas, Priya

Journal:

Critical Reviews in Oncology/Hematology

Year:

2016

Language:

english

File:

PDF, 743 KB

english, 2016

8

Selective mode of action of plumbagin through BRCA1 deficient breast cancer stem cells

Somasundaram, Veena, Hemalatha, Sreelatha K, Pal, Krishnendu, Sinha, Sutapa, Nair, Asha S., Mukhopadhyay, Debabrata, Srinivas, Priya

Journal:

Year:

2016

Language:

english

File:

PDF, 2.51 MB

english, 2016

9

NOS2-derived NO Drives Multiple Pathways of Breast Cancer Progression

Basudhar, Debashree, Somasundaram, Veena, de Oliveira, Graciele Almeida, Kesarwala, Aparna, Heinecke, Julie Lynn, Cheng, Robert Yuk Sing, Glynn, Sharon, Ambs, S, Wink, David A., Ridnour, Lisa A.

Journal:

Antioxidants & Redox Signaling

Year:

2016

Language:

english

File:

PDF, 761 KB

english, 2016

10

Inducible Nitric Oxide Synthase (NOS2) in the Carcinogenesis of Gastrointestinal Cancers

de Oliveira, Graciele Almeida, Cheng, Robert, Ridnour, Lisa A., Basudhar, Debashree, Somasundaram, Veena, McVicar, Daniel W, Monteiro, Hugo Pequeno, Wink, David A.

Journal:

Antioxidants & Redox Signaling

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

11

Macrophage-derived nitric oxide initiates T-cell diapedesis and tumor rejection

Sektioglu, Ibrahim M., Carretero, Rafael, Bender, Noemi, Bogdan, Christian, Garbi, Natalio, Umansky, Viktor, Umansky, Ludmila, Urban, Katharina, von Knebel-Döberitz, Magnus, Somasundaram, Veena, Wink,

Journal:

Year:

2016

Language:

english

File:

PDF, 3.74 MB

english, 2016

12

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer

Basudhar, Debashree, Glynn, Sharon A., Greer, Madison, Somasundaram, Veena, No, Jae Hong, Scheiblin, David A., Garrido, Pablo, Heinz, William F., Ryan, Aideen E., Weiss, Jonathan M., Cheng, Robert Y.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.36 MB

english, 2017

13

Nitric Oxide || NO in Cancer—Carcinogenesis, Metastasis, and Therapy

Somasundaram, Veena

Year:

2017

Language:

english

File:

PDF, 1.55 MB

english, 2017

14

Understanding the tumour microenvironment communication network from a NOS2/COX2 perspective

Basudhar, Debashree, Bharadwaj, Gaurav, Somasundaram, Veena, Cheng, Robert Y S, Ridnour, Lisa A, Fujita, Mayumi, Lockett, Stephen J, Anderson, Stephen K, McVicar, Daniel W, Wink, David A

Journal:

British Journal of Pharmacology

Year:

2018

Language:

english

File:

PDF, 925 KB

english, 2018

15

Brcal Defective Breast Cancer Cells Induce in vitro Transformation of Cancer Associated Fibroblasts (CAFs) to Metastasis Associated Fibroblasts (MAF)

Hemalatha, Sreelatha K., Sengodan, Satheesh Kumar, Nadhan, Revathy, Dev, Jithin, Sushama, Reshma R., Somasundaram, Veena, Thankappan, Ratheeshkumar, Rajan, Arathi, Latha, Neetha Rajan, Varghese, Geetu

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 9.11 MB

english, 2018

16

Role of nitric oxide in pancreatic cancer cells exhibiting the invasive phenotype

Fujita, Mayumi, Somasundaram, Veena, Basudhar, Debashree, Cheng, Robert Y.S., Ridnour, Lisa A., Higuchi, Harumi, Imadome, Kaori, No, Jae Hong, Bharadwaj, Gaurav, Wink, David A.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.47 MB

english, 2019

17

Restricting Diffusive Exchange In Vitro Demonstrates Inos Modulates Hypoxic Gradients in the Tumor Microenvironment

Gilmore, Caroline, Somasundaram, Veena, Scheiblin, David, Heinz, William, Lockett, Stephen, Wink, David

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 46 KB

english, 2019

18

Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level

Somasundaram, Veena, Gilmore, Anne C., Basudhar, Debashree, Palmieri, Erika Mariana, Scheiblin, David A., Heinz, William F., Cheng, Robert.Y.S., Ridnour, Lisa A., Altan-Bonnet, Grégoire, Lockett, Step

Journal:

Year:

2020

Language:

english

File:

PDF, 3.55 MB

english, 2020

19

Studying Triple Negative Breast Cancer Using Orthotopic Breast Cancer Model

Cheng, Robert Y. S., Patel, Nimit L., Back, Timothy, Basudhar, Debashree, Somasundaram, Veena, Kalen, Joseph D., Wink, David A., Ridnour, Lisa A.

Journal:

Journal of Visualized Experiments

Year:

2020

File:

PDF, 687 KB

2020

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